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Tizanidine (Zanaflex) Description
Tizanidine is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
The imidazoline chemical structure of Tizanidine is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Tizanidine was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.
Tizanidine is also known as Tizanidine, Sirdalud.
Generic name of Tizanidine is Tizanidine-Oral.
Brand name of Tizanidine is Tizanidine.
Tizanidine (Zanaflex) Dosage
Tizanidine is available in:
- 2mg Low Dosage
You should take it by mouth.
It usually is taken two or three times a day.
If you want to achieve most effective results do not stop taking Tizanidine suddenly.
Tizanidine (Zanaflex) Missing of dose
Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.
Tizanidine (Zanaflex) Overdose
If you overdose Tizanidine and you don't feel good you should visit your doctor or health care provider immediately.
Tizanidine (Zanaflex) Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.
Tizanidine (Zanaflex) Side effects
Tizanidine has its side effects. The most common are:
- drowsiness
- dizziness
- weakness
- dry mouth
- increased muscle tone or spasms
- sweating
Less common but more serious side effects during taking Tizanidine:
- allergy reactions (urticaria, breathing difficulties, rash, and eruption)
- hallucinations or abnormal behavior; or
- liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual, bleeding or bruising, severe fatigue)
Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.
Tizanidine (Zanaflex) Contra-indications
Do not take Tizanidine if you are allergic to Tizanidine components.
Do not take Tizanidine if you're pregnant or you plan to have a baby, or you are a nursing mother.
Be careful with Tizanidine if you have liver disease, have kidney disease, have low blood pressure.
Be careful with Tizanidine if you are taking medication to treat high blood pressure or birth control pills.
Avoid alcohol.
Do not stop take it suddenly.
Tizanidine (Zanaflex) Frequently asked questions
Q: What does Tizanidine mean?
A: Tizanidine is a muscle relaxant which is used to help relax certain muscles in your body. It relieves the spasms and increases muscle tone caused by medical problems such as multiple sclerosis or spinal injury. This medication is sometimes prescribed for other uses.
Q: What are brand and generic names of Tizanidine?
A: Generic name of Tizanidine is Tizanidine-Oral. Brand name of Tizanidine is Tizanidine.
Q: In what way does Tizanidine operate?
A: Tizanidine is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. The imidazoline chemical structure of Tizanidine is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Tizanidine was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.
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