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Tizan (Zanaflex) Description

Tizan is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Tizan has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Tizan are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.

The imidazoline chemical structure of Tizan is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Tizan was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.

Tizan is also known as Tizanidine, Sirdalud.

Generic name of Tizan is Tizanidine-Oral.

Brand name of Tizan is Tizan.

Tizan (Zanaflex) Dosage

Tizan is available in:

  • 2mg Low Dosage

You should take it by mouth.

It usually is taken two or three times a day.

If you want to achieve most effective results do not stop taking Tizan suddenly.

Tizan (Zanaflex) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Tizan (Zanaflex) Overdose

If you overdose Tizan and you don't feel good you should visit your doctor or health care provider immediately.

Tizan (Zanaflex) Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Tizan (Zanaflex) Side effects

Tizan has its side effects. The most common are:

  • drowsiness
  • dizziness
  • weakness
  • dry mouth
  • increased muscle tone or spasms
  • sweating

Less common but more serious side effects during taking Tizan:

  • allergy reactions (urticaria, breathing difficulties, rash, and eruption)
  • hallucinations or abnormal behavior; or
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual, bleeding or bruising, severe fatigue)

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Tizan (Zanaflex) Contra-indications

Do not take Tizan if you are allergic to Tizan components.

Do not take Tizan if you're pregnant or you plan to have a baby, or you are a nursing mother.

Be careful with Tizan if you have liver disease, have kidney disease, have low blood pressure.

Be careful with Tizan if you are taking medication to treat high blood pressure or birth control pills.

Avoid alcohol.

Do not stop take it suddenly.

Tizan (Zanaflex) Frequently asked questions

Q: What does Tizan mean?

A: Tizan is a muscle relaxant which is used to help relax certain muscles in your body. It relieves the spasms and increases muscle tone caused by medical problems such as multiple sclerosis or spinal injury. This medication is sometimes prescribed for other uses.

Q: What are brand and generic names of Tizan?

A: Generic name of Tizan is Tizanidine-Oral. Brand name of Tizan is Tizan.

Q: In what way does Tizan operate?

A: Tizan is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Tizan has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Tizan are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. The imidazoline chemical structure of Tizan is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Tizan was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.

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