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Sanaflex (Zanaflex) Description

Sanaflex is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Sanaflex has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Sanaflex are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.

The imidazoline chemical structure of Sanaflex is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Sanaflex was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.

Sanaflex is also known as Tizanidine, Sirdalud.

Generic name of Sanaflex is Tizanidine-Oral.

Brand name of Sanaflex is Sanaflex.

Sanaflex (Zanaflex) Dosage

Sanaflex is available in:

  • 2mg Low Dosage

You should take it by mouth.

It usually is taken two or three times a day.

If you want to achieve most effective results do not stop taking Sanaflex suddenly.

Sanaflex (Zanaflex) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Sanaflex (Zanaflex) Overdose

If you overdose Sanaflex and you don't feel good you should visit your doctor or health care provider immediately.

Sanaflex (Zanaflex) Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Sanaflex (Zanaflex) Side effects

Sanaflex has its side effects. The most common are:

  • drowsiness
  • dizziness
  • weakness
  • dry mouth
  • increased muscle tone or spasms
  • sweating

Less common but more serious side effects during taking Sanaflex:

  • allergy reactions (urticaria, breathing difficulties, rash, and eruption)
  • hallucinations or abnormal behavior; or
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual, bleeding or bruising, severe fatigue)

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Sanaflex (Zanaflex) Contra-indications

Do not take Sanaflex if you are allergic to Sanaflex components.

Do not take Sanaflex if you're pregnant or you plan to have a baby, or you are a nursing mother.

Be careful with Sanaflex if you have liver disease, have kidney disease, have low blood pressure.

Be careful with Sanaflex if you are taking medication to treat high blood pressure or birth control pills.

Avoid alcohol.

Do not stop take it suddenly.

Sanaflex (Zanaflex) Frequently asked questions

Q: What does Sanaflex mean?

A: Sanaflex is a muscle relaxant which is used to help relax certain muscles in your body. It relieves the spasms and increases muscle tone caused by medical problems such as multiple sclerosis or spinal injury. This medication is sometimes prescribed for other uses.

Q: What are brand and generic names of Sanaflex?

A: Generic name of Sanaflex is Tizanidine-Oral. Brand name of Sanaflex is Sanaflex.

Q: In what way does Sanaflex operate?

A: Sanaflex is an agonist at (alpha) 2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, Sanaflex has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of Sanaflex are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. The imidazoline chemical structure of Sanaflex is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but Sanaflex was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.

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