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Rocaltrol Description
Rocaltrol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body.
The two known sites of action of Rocaltrol are intestine and bone. Rocaltrol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Rocaltrol may also act on the kidney and the parathyroid glands. Rocaltrol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Rocaltrol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Rocaltrol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Rocaltrol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Rocaltrol produces other independent beneficial effects.
Rocaltrol is also known as Calcitriol.
Rocaltrol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days.
Generic name of Rocaltrol is Calcitriol.
Brand name of Rocaltrol is Rocaltrol.
Rocaltrol Dosage
Rocaltrol is available in:
- 0.25mcg Standard Dosage
Rocaltrol is available in capsules (0.25 mcg) and liquid form.
Capsules must be swallowed whole. Do not crush or chew them.
If you are prescribed the liquid form, use as directed. Follow dosing instructions closely.
Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects.
Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish.
Vitamin D is also obtained from periodic exposure to the sun.
It is important to maintain a well-balanced diet while taking this medication.
Calcium supplements may be recommended in addition to this medication.
If you want to achieve most effective results do not stop taking Rocaltrol suddenly.
Rocaltrol Missing of dose
Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.
Rocaltrol Overdose
If you overdose Rocaltrol and you don't feel good you should visit your doctor or health care provider immediately.
Rocaltrol Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.
Rocaltrol Side effects
Rocaltrol has its side effects. The most common are:
- nausea
- vomiting
- loss of appetite
- constipation
- diarrhea
- stomach pain
- thirst
- weakness
- headache
- bone pain
- dry mouth
- increased urination
Less common but more serious side effects during taking Rocaltrol: allergy reactions (urticaria, breathing difficulties, rash, and eruption).
Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.
Rocaltrol Contra-indications
Do not take Rocaltrol if you are allergic to Rocaltrol components.
Do not take Rocaltrol if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk.
Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects.
Be careful with Rocaltrol if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries).
Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun.
It is important to maintain a well-balanced diet while taking this medication.
Calcium supplements may be recommended in addition to this medication.
It can be dangerous to stop Rocaltrol taking suddenly.
Rocaltrol Frequently asked questions
Q: What is Rocaltrol?
A: Rocaltrol is a form of vitamin D, a fat-soluble vitamin stored in the body. Vitamin D is necessary for normal bone development. This medication is used as a dietary supplement to help prevent and treat rickets (a vitamin D deficiency). It is also used to prevent and treat muscle cramps and certain types of calcium and phosphate disorders (such as with chronic dialysis), and to regulate parathyroid hormone.
Q: How does Rocaltrol work?
A: Rocaltrol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Rocaltrol are intestine and bone. Rocaltrol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Rocaltrol may also act on the kidney and the parathyroid glands. Rocaltrol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Rocaltrol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Rocaltrol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Rocaltrol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Rocaltrol produces other independent beneficial effects. Rocaltrol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days.
Q: What are generic and brand names of Rocaltrol?
A: Generic name of Rocaltrol is Calcitriol. Brand name of Rocaltrol is Rocaltrol.
Q: What should I do in case of overdose?
A: Do not take Rocaltrol in large quantities. In case of Rocaltrol overdosage, you need to visit doctor or health care provider immediately.
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