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Duodopa (Sinemet) Description
Duodopa is a perfect remedy which is used to treat symptoms of Parkinson's disease caused by manganese poisoning, encephalitis, carbon monoxide poisoning. Levodopa is central nervous system agent. Carbidopa is decarboxylase inhibitor. Levodopa gives anti-Parkinson's effect and carbidopa work by protecting levodopa effectiveness.
Generic name of Duodopa is Levodopa and Carbidopa.
Duodopa is also known as Carbidopa-Levodopa, Parcopa, Syndopa.
Brand names of Duodopa are Duodopa, Parcopa, Duodopa CR, Stalevo.
Duodopa (Sinemet) Dosage
Duodopa is available in:
- 10mg + 100mg Low Dosage
- 25mg + 100mg Standard Dosage
- 25mg + 250mg Increased Dosage
Duodopa is available in tablets (10mg + 100mg, 25mg + 100mg, 25mg + 250mg), orally disintegrating tablets, extended-release tablets orally.
Usually tablets and disintegrating tablets are taken 3-4 times a day. The extended-release tablets are usually taken 2-4 times a day. Take Duodopa before meal with water.
Do not take Duodopa if you are under 18.
Do not crush or chew it.
If you want to achieve most effective results do not stop taking Duodopa suddenly.
Duodopa (Sinemet) Missing of dose
Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.
Duodopa (Sinemet) Overdose
If you overdose Duodopa and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Duodopa overdosage: muscle twitches, inability to open the eyes.
Duodopa (Sinemet) Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.
Duodopa (Sinemet) Side effects
Duodopa has its side effects. The most common are:
- nausea
- constipation
- uncontrolled jerking or twitching
- vomiting, insomnia
- decreased appetite
- diarrhea
- extreme sweating
- weakness
- confusion
- seeing things or hearing voices that do not exist (hallucinating)
- migraine
- nervousness
- nightmares
- dry mouth
- lightheadedness
- feeling drowsy
Less common but more serious side effects during taking Duodopa:
- allergy reactions (urticaria, breathing difficulties, rash, and eruption)
- difficulties with swallowing
- tarry and black stools
- pounding, fast, irregular heartbeat
- depression
- bloody vomit
- thoughts of deated
- blood in stools
- symptoms of allergy reaction (hives, difficulties with breathing, rash, swelling, closing )
- huskiness
Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.
Duodopa (Sinemet) Contra-indications
Do not take Duodopa if you are allergic to Duodopa components.
Do not take Duodopa if you are pregnant, planning to become pregnant or breast-feeding.
Be careful using Duodopa if you take iron pills and vitamins containing iron; metoclopramide (such as Reglan); isoniazid (such as Nydrazid, INH); isocarboxazid (such as Marplan); phenytoin (such as Dilantin); antihistamines; risperidone (such as Risperdal); antidepressants (protriptyline (such as Vivactil), clomipramine (such as Anafranil), doxepin (such as Sinequan, Adapin), amitriptyline (such as Elavil), desipramine (such as Norpramin), trimipramine (such as Surmontil), amoxapine (such as Asendin), nortriptyline (such as Pamelor, Aventyl), imipramine (such as Tofranil); selegiline (such as Eldepryl); ipratropium (such as Atrovent); rasagiline (such as Azilect); haloperidol (such as Haldol); high blood pressure medicines; motion sickness, ulcers, irritable bowel disease, nausea, urinary problems, mental illness medications; papaverine (such as Pavabid), tranyllcypromine (such as Parnate) or phenelzine (such as Nardil).
It can be dangerous to use Duodopa if you suffer from or have a history of glaucoma, undiagnosed mole, melanoma, suspicious, phenylketonuria, mental illness; diabetes; heart attacks; asthma; bronchial asthma; endocrine disorder; emphysema; ulcers; active peptic ulcer; hormone problems; irregular heartbeat; kidney, liver, blood vessel, lung or heart disease.
Be careful with Duodopa if you are going to have a surgery.
Do not take Duodopa if you are under 18.
Avoid driving machine.
It can be dangerous to stop Duodopa taking suddenly.
Duodopa (Sinemet) Frequently asked questions
Q: What is Duodopa?
A: Duodopa is a perfect remedy which is used to treat symptoms of Parkinson's disease caused by manganese poisoning, encephalitis, carbon monoxide poisoning.
Q: What should I do in case of dose missing?
A: In case of dose missing you should take your tablet as soon as possible. Do not take double dosage. And if it is right time for the next dosage you should continue your regular schedule of Duodopa taking.
Q: What are Duodopa side effects?
A: Duodopa has its common side effects such as: nausea, constipation, uncontrolled jerking or twitching, vomiting, insomnia, decreased appetite, diarrhea, extreme sweating, weakness, confusion, seeing things or hearing voices that do not exist (hallucinating), migraine, nervousness, nightmares, dry mouth, lightheadedness, feeling drowsy. But in case of rejection of Duodopa ingredients you can experience more serious side effects: difficulties with swallowing, tarry and black stools, pounding, fast, irregular heartbeat, depression, bloody vomit, thoughts of death, red blood in stools, symptoms of allergy reaction (hives, difficulties with breathing, rash, swelling, closing ), huskiness.
Q: What are generic and brand names of Duodopa?
A: Generic name of Duodopa is Levodopa and Carbidopa. Brand names of Duodopa are Duodopa, Parcopa, Duodopa CR, Stalevo.
Q: In what way does it operate?
A: Levodopa is central nervous system agent. Carbidopa is decarboxylase inhibitor. Levodopa gives anti-Parkinson's effect and carbidopa work by protecting levodopa effectiveness.
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