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Duloxetine (Cymbalta) Description

Duloxetine is developed by medical scientists to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors. Duloxetine affects chemicals in the brain that may become unbalanced and cause depression.

Duloxetine is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.

Duloxetine (Cymbalta) Dosage

Duloxetine is available in:

  • 20mg Low Dosage
  • 30mg Standard Dosage
  • 40mg Increased Dosage

Take Duloxetine with a full glass of water with or without food.

It is recommended to take Duloxetine at the same time each day.

Do not crush, chew, break, or open a delayed-release capsule. Swallow the tablet whole.

If you want to achieve most effective results do not stop using Duloxetine suddenly.

Duloxetine (Cymbalta) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Duloxetine (Cymbalta) Overdose

If you overdose Duloxetine and you don't feel good you should visit your doctor or health care provider immediately.

Duloxetine (Cymbalta) Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Duloxetine (Cymbalta) Side effects

Duloxetine has its side effects. The most common are:

  • nausea
  • pain in your upper stomach
  • itching
  • loss of appetite
  • dark urine
  • clay-colored stools
  • jaundice (yellowing of the skin or eyes)
  • feeling like you might pass out
  • agitation
  • hallucinations
  • fever
  • fast heart rate
  • overactive reflexes
  • very stiff (rigid) muscles
  • sweating
  • confusion
  • tremors
  • easy bruising
  • unusual bleeding
  • painful or difficult urination
  • headache
  • trouble concentrating
  • memory problems
  • weakness
  • feeling unsteady
  • loss of coordination
  • seizure
  • shallow breathing or breathing that stops
  • severe skin reaction (swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling)

Less common but still serious side effects during taking Duloxetine:

  • dry mouth
  • drowsiness
  • tired feeling
  • mild nausea or loss of appetite
  • constipation

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Duloxetine (Cymbalta) Contra-indications

Do not take Duloxetine if you are allergic to Duloxetine components.

Do not take Duloxetine if you're pregnant or you plan to have a baby, or you are a nursing mother. This medication can cause birth defects. Tell your doctor right away if you become pregnant during treatment.

Be very careful with Duloxetine if you're pregnant or you plan to have a baby. Do not take Duloxetine if you are breast-feeding.

Do not take Duloxetine together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Duloxetine. After you stop taking Duloxetine, you must wait at least 5 days before you start taking an MAOI.

Duloxetine can be not safety for children and people younger than 18 years old.

Do not take Duloxetine if you have any of these conditions:liver or kidney disease, seizures or epilepsy, a bleeding or blood clotting disorder, glaucoma, bipolar disorder (manic depression), a history of drug abuse or suicidal thoughts.Be careful if you drive or do anything that requires you to be alert. Duloxetine may impair your thinking or reactions.

Avoid alcohol.

It can be dangerous to stop Duloxetine using suddenly.

Duloxetine (Cymbalta) Frequently asked questions

Q: What is Duloxetine?

A: Duloxetine is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Duloxetine affects chemicals in the brain that may become unbalanced and cause depression. Duloxetine is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.

Q: How does Duloxetine operate?

A: Duloxetine is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Duloxetine affects chemicals in the brain that may become unbalanced and cause depression.

Q: What are the symptoms of overdose?

A: Symptoms of Duloxetine overdosage: agitation, hallucinations, fever, overactive reflexes, loss of coordination, extreme drowsiness, vomiting, diarrhea, seizure (convulsions), fast heart rate, feeling light-headed, or fainting.

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