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Amiloride Hydrochlorothiazide (Moduretic) Description

Amiloride Hydrochlorothiazide is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss.

Brand name of Amiloride Hydrochlorothiazide is Amiloride Hydrochlorothiazide.

Amiloride Hydrochlorothiazide (Moduretic) Dosage

Amiloride Hydrochlorothiazide is available in:

  • 5mg + 50mg Standard Dosage

Take Amiloride Hydrochlorothiazide by mouth with food.

Amiloride Hydrochlorothiazide may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

If you want to achieve most effective results do not stop taking Amiloride Hydrochlorothiazide suddenly.

Amiloride Hydrochlorothiazide (Moduretic) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Amiloride Hydrochlorothiazide (Moduretic) Overdose

If you overdose Amiloride Hydrochlorothiazide and you don't feel good you should visit your doctor or health care provider immediately.

Amiloride Hydrochlorothiazide (Moduretic) Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Amiloride Hydrochlorothiazide (Moduretic) Side effects

Amiloride Hydrochlorothiazide has its side effects. The most common are:

  • changes in blood sugar
  • constipation
  • dizziness
  • fatigue
  • headache
  • inflammation of a salivary gland
  • loss of appetite
  • nausea
  • sensitivity to sunlight
  • stomach pain
  • weakness

Less common but more serious side effects during taking Amiloride Hydrochlorothiazide:

  • allergy reactions (urticaria, breathing difficulties, rash, and eruption)
  • dry mouth
  • excessive thirst
  • impotence
  • leg or muscle cramps
  • mental confusion
  • rapid, weak, or irregular heartbeat
  • stomach pain
  • urination problems
  • vomiting
  • yellowing of skin or eyes

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Amiloride Hydrochlorothiazide (Moduretic) Contra-indications

Do not take Amiloride Hydrochlorothiazide if you are allergic to Amiloride Hydrochlorothiazide components or to any ingredient in Amiloride Hydrochlorothiazide or any other sulfonamide (eg, sulfamethoxazole).

Be careful with Amiloride Hydrochlorothiazide if you're pregnant or you plan to have a baby, or you are a nursing mother.

Be careful with Amiloride Hydrochlorothiazide if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.

Be careful with Amiloride Hydrochlorothiazide if you have allergies to medicines, foods, or other substances.

Be careful with Amiloride Hydrochlorothiazide if you have cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, asthma, heart problems, or systemic lupus erythematosus.

Be careful with Amiloride Hydrochlorothiazide if you have elevated blood acid, low folic acid levels, or electrolyte problems, or are dehydrated.

Be careful with Amiloride Hydrochlorothiazide if you take potassium-sparing diuretics (eg, spironolactone), potassium supplements, or salt substitutes containing potassium because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart; cholestyramine or colestipol because they may decrease Amiloride Hydrochlorothiazide 's effectiveness; nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Amiloride Hydrochlorothiazide 's effectiveness and risk of kidney problems may be increased; barbiturates (eg, phenobarbital), certain chemotherapy medicines, corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by Amiloride Hydrochlorothiazide; diazoxide, lithium, or nondepolarizing neuromuscular blockers (eg, pancuronium) because their actions and the risk of their side effects may be increased by Amiloride Hydrochlorothiazide; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of high blood potassium and kidney problems may be increased by Amiloride Hydrochlorothiazide; diabetes medicines (eg, glipizide) or insulin because their effectiveness may be decreased by Amiloride Hydrochlorothiazide.

Do not stop taking Amiloride Hydrochlorothiazide suddenly.

Amiloride Hydrochlorothiazide (Moduretic) Frequently asked questions

Q: What is Amiloride Hydrochlorothiazide?

A: Amiloride Hydrochlorothiazide is used for treating fluid retention (edema) and high blood pressure. It may be used alone or with other medicines.

Q: How should I take Amiloride Hydrochlorothiazide?

A: Amiloride Hydrochlorothiazide is available in tablets (5 mg + 50 mg). Take Amiloride Hydrochlorothiazide by mouth with food. Amiloride Hydrochlorothiazide may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. If you want to achieve most effective results do not stop taking Amiloride Hydrochlorothiazide suddenly.

Q: What should I do in case of overdose?

A: Do not take Amiloride Hydrochlorothiazide tablets in large quantities. In case of Amiloride Hydrochlorothiazide overdosage, you need to visit doctor or health care provider immediately.

Q: How does Amiloride Hydrochlorothiazide operate?

A: Amiloride Hydrochlorothiazide is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss.

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